HPE DL380 Gen11 Server
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Condition
Refurbished
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CPU
2×8GB DDR4 RDIMM 2133MHz
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RAM
noHDD (up to 8 HDD 2.5'' SFF)
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Condition
Refurbished
-
CPU
2×8GB DDR4 RDIMM 2133MHz
-
RAM
noHDD (up to 8 HDD 2.5'' SFF)
-
Condition
Refurbished
-
CPU
2×8GB DDR4 RDIMM 2133MHz
-
RAM
noHDD (up to 8 HDD 2.5'' SFF)
-
Condition
Refurbished
-
CPU
2×8GB DDR4 RDIMM 2133MHz
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RAM
noHDD (up to 8 HDD 2.5'' SFF)
Processor
1 or 2 x 4th or 5th Gen Intel® Xeon® Scalable processors, up to 64 cores per processor, up to 350 W TDP
Memory
DDR5 RDIMM: up to 32 x HPE DDR5 Smart Memory DIMMs (8 TB), speeds up to 5600 MT/s depending on processor and population
Storage controllers
- HPE MR216i-o / MR216i-p
- HPE MR408i-o
- HPE MR416i-o / MR416i-p
- HPE SR932i-p for supported configurations
Drive bays
Front drive support
- Up to 8 or 12 x LFF SAS/SATA/SSD drives
- Up to 8, 16 or 24 x SFF SAS/SATA/SSD drives
- Up to 20 x SFF NVMe drives depending on model
- Up to 12 x EDSFF E3.S drives depending on configuration
Rear drive support
- Up to 6 x SFF rear drives or up to 2 x SFF rear drives depending on configuration
Power supplies
- 800 W Flex Slot Platinum or Titanium
- 1000 W Flex Slot Titanium
- 1600 W Flex Slot Platinum
- 1800 W-2200 W Flex Slot Titanium
Cooling and fans
Hot-plug redundant fans; standard or high-performance fan kit depending on model
Dimensions
- Height: 87.5 mm (3.44 inches)
- Width: 448.0 mm (17.64 inches)
- Depth: up to 732.5 mm (28.84 inches)
- Weight: up to 37 kg (81.57 lb)
Form factor
2U rack server
Embedded management
- HPE iLO 6 Standard with Intelligent Provisioning
- HPE OneView Standard
- HPE iLO Advanced, optional
- HPE OneView Advanced, optional
- HPE Compute Ops Management
- Redfish API support
Security
- UEFI Secure Boot and Secure Start
- Immutable Silicon Root of Trust
- Intel® Software Guard Extensions (SGX), where supported
- TPM 2.0 support
- IDevID certificates installed by default
- Secure Recovery and Runtime Firmware Verification with HPE iLO Advanced Premium Security Edition
- Optional Trusted Supply Chain, iLO security modes, chassis intrusion detection and bezel locking kits
Networking
- PCIe adapter and OCP 3.0 network options
- 1 Gb, 10 Gb, 10/25 Gb, 100 Gb or 200 Gb options depending on model
Ports
Front ports
- 1 x iLO Service Port
- 1 x USB 3.2 Gen1
- 1 x USB 2.0, optional
- 1 x DisplayPort, optional
Internal ports
- 1 x USB 3.2 Gen1
- 1 x USB 2.0
Rear ports
- 1 x dedicated 1GbE iLO Management Port
- 2 x USB 3.2 Gen1
- 1 x VGA
- 1 x Serial port, optional
PCIe expansion
Up to 8 x PCIe Gen5 slots and 2 x OCP 3.0 slots
Optical drive
Optional DVD-ROM via Universal Media Bay; external support only
Operating systems and virtualization
- Microsoft Windows Server 2019, 2022, 2025
- VMware ESXi 7.0 U3; VMware ESXi 8.0, 8.0 U1, 8.0 U2, 8.0 U3; VMware ESX 9.0, 9.1
- Red Hat Enterprise Linux 8.6, 9.0, 10.0; 5th Gen Intel® Xeon® Scalable configurations require RHEL 8.8 or RHEL 9.2 minimum
- SUSE Linux Enterprise Server 15 SP4; SLES 16 and SLES 15 SP5 QU1 for 5th Gen Intel® Xeon® Scalable configurations
- SUSE Linux Enterprise Micro 5.3; SUSE Linux Micro 6.2 and SLE Micro 5.5 for 5th Gen Intel® Xeon® Scalable configurations
- Canonical Ubuntu 20.04.5 LTS, 22.04 LTS, 24.04 LTS
- Oracle Linux 8.10/9.0 for 4th Gen Intel® Xeon® Scalable; Oracle Linux 8.10/9.3/10.0 for 5th Gen Intel® Xeon® Scalable
HPE ProLiant DL380 Gen11 overview
HPE ProLiant DL380 Gen11 is a versatile 2U, dual-socket rack server for enterprise workloads that need a strong balance of compute performance, memory capacity, storage flexibility and PCIe Gen5 expansion. As an HPE DL380 Gen11 2U rack server, it is based on 4th or 5th Generation Intel Xeon Scalable processors, DDR5 Smart Memory and HPE iLO 6 management.
The HPE ProLiant DL380 Gen11 server is suitable for virtualization, VDI, containers, databases, data management, software-defined storage, backup infrastructure and selected GPU-accelerated workloads. It should be treated as a flexible mainstream enterprise platform, not as a narrow-purpose or entry-level server. Compared with previous DL380 generations, Gen11 brings a newer processor platform, DDR5 memory, PCIe Gen5 I/O and updated HPE management capabilities.
When to choose HPE ProLiant DL380 Gen11
Choose HPE ProLiant DL380 Gen11 when the workload needs a standard 2U dual-socket enterprise platform with room for growth. It is a good fit for virtualization clusters, private cloud nodes, container platforms, business applications, database servers, analytics systems and infrastructure roles where compute, RAM, storage and network options must be balanced carefully.
Compared with a 1U server such as HPE ProLiant DL360 Gen11, the HPE DL380 Gen11 gives more physical space for drives, PCIe cards, GPU options, airflow and serviceability. This can be useful when local storage, accelerator support or long-term configuration flexibility matters more than maximum rack density.
The HPE DL380 Gen11 configuration should be validated carefully for processor generation, memory population, drive cage layout, storage controller, risers, NICs, power supplies, fans and cooling. This is especially important for NVMe, EDSFF, rear-drive and GPU configurations. If the project requires AMD processors, compare with HPE ProLiant DL385 Gen11; if the project requires a denser 1U Intel platform, compare with HPE ProLiant DL360 Gen11.
Chassis and drive bay options
HPE ProLiant DL380 Gen11 supports several chassis and drive bay layouts. The right option depends on whether the server is being configured for balanced virtualization, high-density SSD storage, capacity-oriented HDD storage, NVMe performance or accelerator-heavy workloads.
| Chassis option | Best for | Comment |
|---|---|---|
| HPE DL380 Gen11 8SFF | Balanced virtualization, business applications and mixed enterprise workloads | Supports SAS, SATA and NVMe options depending on the selected backplane and controller. It can be expanded with selected front and rear SFF drive options. |
| HPE DL380 Gen11 24SFF | High-density 2.5-inch SSD or hybrid storage configurations | Supports SAS, SATA and NVMe drive options, with rear SFF drive options available in selected configurations. |
| HPE DL380 Gen11 8LFF | Capacity-oriented workloads with some flexibility for additional SFF or rear drives | Useful when 3.5-inch HDD capacity is important, but the exact front and rear drive layout must be checked before ordering. |
| HPE DL380 Gen11 12LFF | Backup repositories, archive storage, file services and capacity-focused infrastructure | Can be configured with additional rear LFF drives in selected builds, making it suitable for large local capacity. |
| HPE DL380 Gen11 EDSFF NVMe configurations | High-performance NVMe storage and dense flash-oriented configurations | EDSFF is intended for NVMe-focused builds. Final drive count and compatibility depend on the selected EDSFF CTO model or FIO bundle, backplane, cabling, risers, cooling and storage options. |
For capacity workloads, LFF configurations are usually the practical starting point. For latency-sensitive databases, virtualization datastores and high-IO workloads, SFF SSD, U.3 NVMe or EDSFF NVMe configurations should be considered. NVMe and EDSFF support should not be assumed from the server model name alone; it depends on the exact backplane, drive cage, cabling, controller and CTO configuration.
Final drive compatibility depends on the selected chassis, backplane, storage controller, cables, risers, cooling configuration and HPE support matrix.
Recommended HPE ProLiant DL380 Gen11 configurations by workload
| Workload | Recommended focus |
|---|---|
| Virtualization / private cloud | Balanced dual-socket CPU configuration, large DDR5 memory pool, SSD or NVMe storage where needed, redundant networking and room for future RAM expansion. |
| VDI | High RAM density, predictable CPU performance, fast storage and validated GPU options when graphics acceleration is required. |
| Containers / Kubernetes | Balanced CPU and RAM, reliable boot media, fast local SSD where needed and redundant network connectivity for cluster traffic. |
| Databases / data management | Processor choice matched to licensing and query profile, enough RAM for cache, low-latency SSD or NVMe storage and protected storage design. |
| Backup / archive | 8LFF or 12LFF chassis, capacity HDDs, moderate CPU/RAM and network throughput sized for backup windows and restore requirements. |
| Software-defined storage / HCI | Drive layout, HBA/JBOD or controller mode, network bandwidth and CPU/RAM sized for the selected SDS platform. |
| GPU-accelerated workloads | Validated GPU model, risers, power cables, high-performance fans, cooling limits and memory sizing checked before purchase. |
| Mixed enterprise workloads | Balanced CPU, RAM, storage and NIC choices, with headroom for failover, maintenance and growth. |
The HPE DL380 Gen11 configuration should be chosen around the main reason for selecting a 2U enterprise server: flexible storage, strong dual-socket compute, DDR5 memory capacity, PCIe Gen5 expansion and long-term serviceability.
How to choose CPU, RAM, RAID and storage
HPE ProLiant DL380 Gen11 supports 4th and 5th Generation Intel Xeon Scalable processors depending on the selected server configuration. Higher core counts help virtualization, containers, VDI and multi-user services, while higher clock speed can matter for databases and applications that are sensitive to per-core performance. Processor choice should also account for software licensing, especially for VMware, Windows Server, Microsoft SQL Server, Oracle and other commercial platforms.
Do not treat 4th Gen and 5th Gen Intel Xeon configurations as freely interchangeable. HPE notes that field upgrade from a 4th Generation Intel Xeon processor platform to a 5th Generation Intel Xeon processor platform is not supported. If a 5th Gen Xeon build is required, confirm the processor generation and system board at the time of purchase.
RAM planning should start with VM density, database cache requirements, container scheduling, failover design and future growth. HPE ProLiant DL380 Gen11 supports HPE DDR5 Smart Memory with up to 32 DIMM slots, 16 DIMM slots per processor, depending on the selected chassis and configuration. Maximum memory capacity can reach up to 8 TB with 32 × 256 GB RDIMM in supported chassis layouts. Some drive bay layouts can reduce the number of available DIMM slots, so the final memory layout should be validated before ordering.
Hardware RAID is appropriate for classic server deployments with protected local arrays. HBA or JBOD mode is usually preferred for ZFS, Ceph, VMware vSAN, Proxmox/ZFS and other software-defined storage platforms when the software layer manages disks directly. HPE boot options such as NS204i-u, where available, can separate OS or hypervisor boot from the main data drives.
For storage, LFF HDDs are capacity-oriented and are suitable for backup, archive and file services. SFF SSDs are better for application responsiveness and mixed virtualization workloads. NVMe and EDSFF options are better for latency-sensitive databases, high-IO virtualization and analytics, but only when the exact chassis, backplane and CTO configuration support the required drive type.
HPE ProLiant DL380 Gen11 vs related HPE models
| Model | When to consider |
|---|---|
| HPE ProLiant DL360 Gen11 | Choose DL360 Gen11 when 1U density is more important than maximum local storage, PCIe expansion or GPU flexibility. |
| HPE ProLiant DL365 Gen11 | Choose DL365 Gen11 when a 1U AMD EPYC platform is preferred for dense compute or AMD-based standardization. |
| HPE ProLiant DL385 Gen11 | Choose DL385 Gen11 when a 2U AMD EPYC platform is required for high core count, memory bandwidth or AMD-based infrastructure standards. |
| HPE ProLiant DL560 Gen11 | Choose DL560 Gen11 when the workload needs a four-socket platform and the application or licensing model justifies higher CPU and memory scale in 2U. |
| HPE ProLiant DL380 Gen10 Plus | Consider DL380 Gen10 Plus when a previous-generation DDR4 and PCIe Gen4 platform is sufficient and acquisition cost is the main priority. |
HPE ProLiant DL380 Gen11 is the right reference point when the requirement is an Intel-based HPE Gen11 2U enterprise server with broad configuration flexibility. It is not the same platform as DL380 Gen10 Plus and should not be described only as a minor refresh.
Summary: is HPE ProLiant DL380 Gen11 the right server for your workload×
HPE ProLiant DL380 Gen11 is a strong 2U enterprise server for virtualization, VDI, containers, databases, software-defined storage, backup and mixed infrastructure workloads. Choose it when you need an Intel Xeon-based HPE Gen11 platform with DDR5 memory, PCIe Gen5 expansion, flexible storage layouts and HPE management features. Consider DL360 Gen11 for 1U density, DL385 Gen11 for AMD EPYC-based 2U infrastructure, DL560 Gen11 for four-socket scale or DL380 Gen10 Plus when a previous-generation platform is enough. Before purchase, confirm CPU generation, RAM population, storage layout, RAID/HBA mode, network, risers, cooling, PSU and warranty requirements.
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